Loxosceles gaucho venom-induced acute kidney injury--in vivo and in vitro studies.
BACKGROUND: Accidents caused by Loxosceles spider may cause severe systemic reactions, including acute kidney injury (AKI).There are few experimental studies assessing Loxosceles venom effects on kidney function in vivo.METHODOLOGY/PRINCIPAL FINDINGS: In order to test Loxosceles gaucho venom (LV) nephrotoxicity and to assess some of the possible me